（2025年11月更新）

一、个人简介

魏丽杰，女，博士研究生，毕业于中国科学院大学，讲师，硕士生导师。连云港市“521工程”第三层次培养对象。近年来，研究成果在《Carbohydrate Polymers》 《International Journal of Biological Macromolecules》 《Molecules》《Starch‐Stärke》《Polymers》等国外学术期刊发表论文20余篇，其中一作发表SCI 9篇，获得中国发明专利2件。主持市厅级纵向课题2项，横向课题若干项，江苏省海洋资源开发研究院开放课题1项。作为科研骨干参与省重点研发计划1项，省自然科学基金1项。

E-Mail: weilijie0505@163.com

通讯地址：江苏连云港市苍梧路59号江苏海洋大学海洋食品与生物工程学院

二、研究方向

主要针对壳聚糖、菊糖等生物多糖基多功能材料的制备，包括抑菌、抗氧化、环境响应型纳米体系的构建，探究其在医药、食品、农业等领域的应用。

三、代表性成果

（1）项目

[1] ROS/pH双响应型壳聚糖基NDDS构建及其在RA治疗中的联合调控研究，连云港市科学技术局市重点研发计划，CG2534。

[2] 基于ROS/pH双重响应纳米系统的RA协同治疗与作用机制研究，连云港市第六期“521高层次人才培养工程”， LYG065212025088.

科研项目

（2）论文

[1] Lijie Wei, Qing Li, Yuan Chen, Jingjing Zhang, Yingqi Mi, Fang Dong, Chunqing Lei, Zhanyong Guo. Enhanced antioxidant and antifungal activity of chitosan derivatives bearing 6-O-imidazole-based quaternary ammonium salts. Carbohydrate Polymers, 2019, 206, 493-503.

[2] Lijie Wei, Wenqiang Tan, Gang Wang, Qing Li, Fang Dong, Zhanyong Guo. The antioxidant and antifungal activity of chitosan derivatives bearing Schiff bases and quaternary ammonium salts. Carbohydrate Polymers, 2019, 226, 115256.

[3] Lijie Wei, Jingjing Zhang, Wenqiang Tan, Gang Wang, Qing Li, Fang Dong, Zhanyong Guo. Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes. International Journal of Biological Macromolecules, 2021, 179, 292-298.

[4] Lijie Wei, Haishan Sui, Jingjing Zhang, Zhanyong Guo. Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate. International Journal of Biological Macromolecules, 2021, 186, 47-53.

[5] Lijie Wei, Yingqi Mi, Jingjing Zhang, Qing Li, Fang Dong, Zhanyong Guo. Evaluation of quaternary ammonium chitosan derivatives differing in the length of alkyl side-chain: Synthesis and antifungal activity. International Journal of Biological Macromolecules, 2019, 129, 1127-1132.

[6] Lijie Wei, Qing Li, Wenqiang Tan, Fang Dong, Fang Luan, Zhanyong Guo. Synthesis, characterization, and the antioxidant activity of double quaternized chitosan derivatives. Molecules, 2017, 22, 501.

[7] Lijie Wei, Jingjing Zhang, Fang Luan, Wenqiang Tan, Qing Li, Fang Dong, Zhanyong Guo. Synthesis, characterization, and the antifungal property of aminoethyl chitosan quaternary ammonium salts. Starch‐Stärke, 2018, 70, 1700266.

[8] Lijie Wei, Yuan Chen, Wenqiang Tan, Qing Li, Guodong Gu, Fang Dong, Zhanyong Guo. Synthesis, characterization, and antifungal activity of pyridine-based triple quaternized chitosan derivatives. Molecules, 2018, 23, 2604.

[9] Lijie Wei, Wenqiang Tan, Jingjing Zhang, Yingqi Mi, Fang Dong, Qing Li, Zhanyong Guo. Synthesis, characterization, and antifungal activity of Schiff bases of inulin bearing pyridine ring. Polymers, 2019, 11, 371.

（3）专利

[1] 一种双席夫碱壳聚糖衍生物及其制备方法和应用，授权号：ZL201811569886.6

[2] 一种用于筛查和定量分析复方甘草片中防腐剂成分的测定方法，授权号：ZL202110531866.5